Before you take any steps please back up your files and database. The plugin works only with default CMS pattern. If you manually changed CMS patterns, the plugin might not help you.
There is currently no plugin available for automatic CDN integration with Kirby. You need to change manually the path for your CSS and JS files in the header.php but there is the Kirby GetImages plugin for your images. For more details visit https://github.com/RobBrazier/kirby-getimage
Integration has been completed! We highly recommend you to check the HTML code of your webpage to ensure that URLs have been rewritten properly from your original ones to CNAME from the control panel.
To do that press F12 or open Developers Tools in your browser, choose the Network tab and refresh the page. All static files should have your CNAME in URLs.